file access denied

> while trying to access certain files I get the message :
> Access is denied.
> Make sure the disk is not full or write-protected and
> that the file is not currently in use.
>
> However, the disk is neither full nor write-protected and
> the file is not in use by anyone else.
>
> how to delete these type of files right now cant do
> anything with them
>
> i am administrator on this computer