Vista Business Activation and Imaging

I plan on creating a creating a Vista Business stnadardized image for our
company and have the following question.

(1) I will be activating the "master" image prior to ghosting or using
imagex (more likely imagex) - CAN I use this activated image then sysprep it
and THEN apply it to my other machines?

(2) Basically, since I am applying it on our other machines which may be
different in model, will it require be to RE-Activate?

We use MAKS.

Thank you.