Vista Security and Various Applications not working

I'm testing Vista for the company and mostly it is fine. Our legacy
applications seem to run fine which was a great surprise. My problem is with
everything else. I keep having troubles becuase some key or other in the
registry will nto let me register a driver or add a typelib. the programs
install, but when you go to run them I get various errors related to typelib
problems. Most I fiureed out I have to take ownship of a key and then I
give the administrators access. This was true for Roxio EMC and SQL Server
2005 admin tools. Both took days to make work. I've been working on getting
the TechNet library applications to run for days now working with another
discussion group. I find that if there is a permission for TrustedInstaller I
can't do anything and I'm a domain admin. IS ther somway to figure out who
the TraustedInstaller is? That way I would always logon as them when I
install something and run it for the first time so all the libraries load.
I've logged onto this PC with every logon I've ever used on it to no avail.
In the case of TechNet it is a olb that I cannot register. Is there a book
or whitepaper that makes clear what the secuirty implications are for
installation Microsoft and 3rd party apps so taht anyone on the PC can run
them?
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Bettie